Bluestem oral care Toothpaste with our patent-pending coactiv+ technology is scientifically formulated to freshen breath, fight plaque, reduce tartar, and promote good oral hygiene. Made from 100% food-grade ingredients, our toothpaste is safe and effective for every day use. Coactiv+ is a unique formulation that breaks down biofilm where harmful bacteria multiply. Sold in combination with a dual head toothbrush to reach both the inside out outside of the teeth at the same time.